3. GONOCOCCAL-ASSOCIATED IRIDOCYCLITIS (ANTERIOR UVEITIS): A LITERATURE REVIEW

GONOCOCCAL-ASSOCIATED IRIDOCYCLITIS (ANTERIOR UVEITIS):
A LITERATURE REVIEW

Y.V. Serdyukova, M.T. Okilova
Asian International University named after Satkynbai Tentishev
Department of Surgical Disciplines
Kant, Kyrgyzstan

Abstract
Background. Ocular gonococcal infection in adults is rare but potentially sight-threatening
due to its rapid progression and risk of corneal complications. Anterior uveitis (iridocyclitis) in the
context of Neisseria gonorrhoeae is frequently underrecognised and misclassified as non-specific
uveitis without consideration of an STI aetiology.
Aim. To summarise current evidence on the clinical spectrum, diagnostic approach, and
treatment principles of gonococcal-associated anterior uveitis/iridocyclitis.
Materials and methods. A narrative literature review was conducted using PubMed/PMC
databases (1987–2026). Search terms: Neisseria gonorrhoeae, gonococcal, ocular, uveitis,
iridocyclitis, anterior chamber reaction. Inclusion criteria: laboratory-confirmed gonococcal
aetiology and description of anterior segment status. Twenty-three sources were analysed.
Results. Isolated gonococcal iridocyclitis is rare; uveitic signs more commonly occur as a
component of severe keratoconjunctivitis. Early laboratory confirmation (NAAT or culture) and
immediate systemic ceftriaxone remain the cornerstones of sight-preserving management.
Conclusion. Gonococcal iridocyclitis requires a multidisciplinary approach involving
ophthalmology, dermatovenereology and infectious disease specialists. Growing antimicrobial
resistance in N. gonorrhoeae mandates ongoing surveillance and protocol updates.
Keywords: gonorrhea, Neisseria gonorrhoeae, iridocyclitis, anterior uveitis,
keratoconjunctivitis, diagnosis, ceftriaxone.